Dry Powder Inhaler (DPI)
A Dry Powder Inhaler (DPI) is designed to deliver a precise measured dose of medication by breath activation.
The test procedure measures aerodynamic particle size distribution of the drug leaving the device and can define the manner in which the aerosol deposits in the respiratory tract during inhalation. Aerosol characterization is often used in judging inhaler performance and is particularly relevant in the development of inhalation formulations during research, production, quality assurance and equivalency testing.
The results of characterizations using multi-stage cascade impaction techniques are used for the determination of fine particle fraction or fine particle dose which may be correlated to the dose or fraction of the drug penetrating the lungs during patient inhalation. Other instruments collect and measure doses per container.
Specified test applications and various systems described meet both the pharmaceutical industry and its legislators.
